Chemical Laboratory Instrumentation: Operation, Quality and Safety of Equipment

Details :

Efficient use of advanced operations and instruments in the chemical laboratory are vital tools to solve any laboratory problem. The course provides basic laboratory analysis methods and troubleshooting techniques for the most used instruments. Laboratory quality management according to an international standard is also important to enhance the laboratory system and environment. In addition, safety regulations are increasingly emphasizing the importance of management commitment and employee involvement in managing risks. The aim of this course is to enrich and advance the skills and knowledge of participants to understand laboratory techniques, quality laboratory requirements and the procedures of safety methods.


This course will links together an understanding of performance characteristics with an appreciation of the limitations imposed by analytical instrument design, leading to the interplay of the validation and qualification processes within quality assurance systems. The course includes unique framework of topics covers the major instrumental techniques of spectrophotometry, chromatography, capillary electrophoresis and atomic emission spectroscopy. The use of case studies, exercises and practical applications, will help the participants to develop a thorough understanding of the various concepts that underpin the different techniques.


This course will cover the major operations performed in an industrial chemical laboratory. It will describe the major equipment used in the chemical laboratory, their operations, validations, calibrations and maintenance. The course will concentrate on Standard Operation Procedures (SOP) which includes development, revisions, standards and implementations. Various Quality standards will be discussed. However, the course will concentrate on ISO 17025:2005. Finally, the course will demonstrate the safety practices and its critical impact in an industrial chemical laboratory. OSHA standards and regulations will be discussed and related videos will be shown to attendees.


In addition to the updated knowledge provided to attendees during the course period, each attendee will go back to his/her laboratory equipped with an outstanding manual that includes typical SOP’s that can be modified and used within attendee’s laboratory.


This outstanding course is a MUST for every laboratory professional. The updated knowledge and techniques covered during the 5 days of this training, will dramatically improve not only the attendee’s skills, but will also improve the performance of the attendee’s laboratory as a whole. However, if you are looking to improve the performance of your laboratory, then you have to commit yourself to pass the knowledge gained in this training to your subordinates and colleagues back in your laboratory as we will give you all the tools needed for this purpose; knowledge, skills, manual, power point slides, videos, Standard Operation Procedures (SOP), forms and standards.



Ø  Upon successful completion of this course, the delegates will be able to:


    Apply an in-depth knowledge and skills in the chemical laboratories including analytical instrumentation, analytical techniques, laboratory equipment, operational procedures, management style, method validation, quality and safety management systems


     Use the major analytical laboratory instruments and equipment and understanding their performance characteristics, capabilities, accuracies, reliabilities, speed and limitations including UV/VIS, flow injection, infrared/raman spectroscopy, ion chromatography, pH probes, and gas chromatography


    Calibrate and certify various laboratory instruments and calculate uncertainty and random error

     Impart the participants fundamental techniques of chemical laboratory


    Understand how to validate the analytical method


    Analyse the instrument performance characteristics which includes types and interaction between different characteristics


    Prepare and handle sample for different analytical instrumentations and extract analyses from complex matrices


     Develop and modify the laboratory standard operation procedures (SOP) and interpret the requirements of the ISO 17025 quality system


     Explain the flow of work and major concerns related to the Industrial Chemical Laboratory

     Carryout sampling and sample handling


     Increase knowledge about laboratory equipment and instruments such as mechanical measurements, chemical analysis and process analysers


     Discuss nuclear magnetic instruments covering its theory, NMR spectroscopy, design and performance idea


     Illustrate NMR applications, multi-dimensional NMR spectroscopy and solid-state NMR spectroscopy


     Perform chemical laboratory operations and gain good skills of developing and modifying the laboratory Standard Operating Procedures (SOP)


    To understand the laboratory quality requirements and appreciate the need for a quality system according to the International Standards Organization ISO 17025 standard


    To use the international Guide to Lab Quality for accreditation standard methods


     Employ the safety and environmental requirements for chemical laboratory as per OSHA standard

This course provides an overview of all significant aspects and considerations of modern chemical laboratory for those who are involved in analytical instrumentation, equipment calibration, operations, quality and safety including laboratory managers, engineers, chemists, scientists and other laboratory technical staff. This course is also suitable for instrumentation engineers and other instrumentation staff who are in-charge of instrumentation calibration and maintenance

Day 1:

ü Introduction to chemical laboratory technique

     ü Methods of analysis

     ü Basic laboratory technique: sample preparation, analytical measurement,         fundamental concepts, chemical equation, acidity of solution, buffers

ü Preparation of chemicals

     ü Titration methods

    ü Manipulation methods: solid phase extraction and derivatization

    ü Chromatography technique

    ü Gas chromatography (inject system, column, detector types)


Day 2:


ü High performance liquid chromatography: mobile phase, pumping system, sample inject system, column, detector types

ü Data management software

    ü Analytical retention process

    ü Spectroscopy technique and molecule identification

    ü Spectroscopy - infrared absorption, nuclear magnetic resonance , mass ,        UV/VIS, flow injection, UV/IR absorption, infrared/raman spectroscopy, X-Ray         and electron

    ü ion chromatography, pH probes and gas chromatography

    ü Atomic absorption

    ü NMR spectroscopy, design and performance idea

    ü NMR applications

           ümulti-dimensional NMR spectroscopy

     ü solid-state NMR spectroscopy



Day 3:

     ü Instruments troubleshooting: column contamination, broad in the peak         bandwidth, ghost peaks, system peak, contamination in the inlet filter, change         solvent in mobile phase (HPLC), interferences in the AAS, detector         contamination

ü Quantitative methods: calibration methods, external and internal standards, outliers test, determination of analytes concentration, standard addition method, error in quantitative analysis, confidence limits, detection limit, repeatability and reproducibility

         ü Lab quality management requirements ISO 17025

         ü Lab quality technical requirements ISO 17025

         ü Validation of analytical methods

         ü Laboratory accreditation

         ü Laboratory standard safety guideline

         ü Identification of hazardous chemicals

         ü Safe work practices and procedures


Day 4:

         ü Management of compressed gases


ü             üTransporting of chemicals


ü         üElectrical safety


ü        ü Practical Session/Site Visit


Day 5:

ü Guidelines for good laboratory practices

       ü OSHA standard

     ü Laboratory fire protection

     ü Storage and handling of flammable and combustible liquids

     ü Laboratory waste disposal

     ü Spill and hazard waste management laboratory first aid

  • All lectures are in colorful presentation
  • All lectures are interspersed with interactive discussion
  • All lectures include group discussion, case history and exercises
  • Actual major incidents as well as industry experience are reviewed
  • Participants receive a multicolor course manual
  • Pictures of real incidents and case history are shown
  • Videos on the subject are shown

daily 09:00 – 14:00