Chemical Laboratory Instrumentation: Operation, Quality and Safety of Equipment
Details :
Modern chemical laboratories rely on advanced
instrumentation, strict quality systems, and rigorous safety practices to
ensure accurate and reliable results. This course provides a comprehensive
understanding of laboratory analytical techniques, instrumentation operation,
troubleshooting, quality assurance based on ISO standards, and safe handling of
chemicals and equipment.
Participants will gain both theoretical knowledge and
practical insights into operating laboratory instruments such as
chromatography systems, spectroscopy tools, and analytical equipment, while
maintaining compliance with international quality and safety standards.
Ø By the end of this course, participants will be able to:
- Understand
core chemical laboratory techniques and analytical methods
- Operate
and interpret results from chromatographic and spectroscopic
instruments
- Apply quantitative
analysis and calibration techniques
- Troubleshoot
common laboratory instrumentation issues
- Implement
ISO 17025 laboratory quality requirements
- Ensure
compliance with laboratory safety and OSHA standards
- Manage
chemical hazards, waste, and emergency situations effectively
- Laboratory
Analysts & Technicians
- Chemists
and Quality Control Personnel
- Process
and Production Engineers
- HSE
Officers working in laboratories
- Research
& Development Staff
Day 1: Fundamentals of Chemical Laboratory Techniques
& Chromatography
Session 1
- Introduction
to chemical laboratory techniques
- Methods
of analysis (qualitative vs quantitative)
- Basic
laboratory techniques:
- Sample
preparation
- Analytical
measurement
- Fundamental
concepts & chemical equations
- Acidity,
pH, and buffer systems
Session 2
- Preparation
of chemicals and reagents
- Titration
methods (acid-base, redox, complexometric)
- Manipulation
techniques:
- Solid
Phase Extraction (SPE)
- Derivatization
- Introduction
to chromatography:
- Principles
and types
- Gas
Chromatography (GC):
- Injection
systems
- Columns
- Detector types
Day 2: Advanced Instrumentation & Spectroscopy
Session 1
- High
Performance Liquid Chromatography (HPLC):
- Mobile
phase selection
- Pumping
systems
- Sample
injection systems
- Columns
and detectors
- Data
management software in laboratories
- Analytical
retention processes
Session 2
- Spectroscopy
techniques and molecular identification:
- UV/Vis
spectroscopy
- Infrared
(IR) and Raman spectroscopy
- Mass
spectrometry
- X-ray
and electron spectroscopy
- Flow
injection analysis
- Ion
chromatography and pH probes
- Atomic
Absorption Spectroscopy (AAS)
- Nuclear
Magnetic Resonance (NMR):
- Design
and operating principles
- Applications
- Multi-dimensional
NMR
- Solid-state NMR
Day 3: Troubleshooting, Quantitative Analysis &
Quality Systems
Session 1
- Instrument
troubleshooting:
- Column
contamination
- Peak
broadening
- Ghost
peaks and system peaks
- Inlet
filter contamination
- Mobile
phase issues (HPLC)
- AAS
interferences
- Detector
contamination
- Quantitative
analysis methods:
- Calibration
techniques
- External
vs internal standards
- Standard
addition method
Session 2
- Statistical
analysis in laboratory work:
- Outlier
tests
- Error
analysis
- Confidence
limits
- Detection
limits
- Repeatability
and reproducibility
- Laboratory
Quality Systems:
- ISO
17025 requirements (management & technical)
- Validation
of analytical methods
- Laboratory
accreditation
- Introduction
to laboratory safety:
- Hazard
identification
- Safe work practices
Day 4: Laboratory Safety & Practical Application
Session 1
- Management
of compressed gases
- Safe
transport of chemicals
- Electrical
safety in laboratories
Session 2
- Practical
Session / Site Visit
- Instrument
observation (HPLC, GC, AAS, etc.)
- Safety
systems review
- Hands-on
discussion on operational challenges
Day 5: Laboratory Safety Standards & Emergency
Response
Session 1
- Guidelines
for Good Laboratory Practices (GLP)
- OSHA
laboratory standards
- Laboratory
fire protection systems
- Storage
and handling of:
- Flammable
liquids
- Combustible
chemicals
Session 2
- Laboratory
waste management:
- Hazardous
waste disposal
- Chemical
waste segregation
- Spill
management procedures
- Emergency
response and laboratory first aid
- Interactive
lectures
- Case
studies from real laboratory scenarios
- Group
discussions
- Instrument
demonstrations (if available)
- Practical
session / site visit
- Problem-solving
and troubleshooting exercises
daily 09:00 – 14:00

